Whether we like it or not, machines have become an indispensable part of a man’s life. There are those who say that humans are enslaved to modern technology and reject progress and new technological achievements on principle, while, on the other hand, fanatics of new trends simply must have not only the latest necessary and useful tools but every gadget and gimmick as well. Oftentimes we put our lives into the virtual or quite literal hands of machines when we accept that they make life-or-death decisions for us. They are considered with philosophical or ethical attitude when we ask questions if artificial intelligence is real, or talk about thinking machines. They enable us to study secrets of DNA on the micro, and the whole Universe on the macro scale. This conference covers the whole spectrum of theory and practice of man-machine interactions, focusing on automatic knowledge acquisition and processing employed in decision support systems, constantly evolving computational techniques, specialised user interfaces accessible also for disabled, and artificial intelligence methods applied in such areas as computer vision or biosciences. The ICMMI Conference is inherently interdisciplinary as it aims to bring together scientists working in all these fields, providing an international forum for exchanging ideas, setting questions and problems for discussion, sharing the experience and knowledge among wide community of scientists.