Hosted over two days, this international conference will provide an exclusive opportunity to gain new insight on small molecule-protein fragments, IMI Open PHACTS project for data mining work flows, and structure-based models combining hit finding strategies of fragment leads.Inspiring talks will also highlight developments in the quality control of misfolded proteins, solvent effects, and protein-ligand stability; identifying whether the bound conformation of protein-ligand structure gives the lowest energy state and the impact of drug design.Join us for a keynote address on reviving covalent drug design in oncology from Pfizer, and a case study session on target validation of NCE’s through fragment screening and opportunities for antibodies as guidance tools from UCB.