Hot-melt extrusion (HME) has increased in prominence for the pharmaceutical industry as an approach to develop solid dispersion dosage forms that enhance solubility/bioavailability of poorly soluble drugs. SMi’s Hot-Melt Extrusion for Pharmaceutical Applications masterclass reviews HME technology, focussing on use of twin-screw extruders and demonstrates the advantages for pharmaceutical applications. Beginning with the initial mixing of APIs, the session will move sequentially through processing, cooling, milling and final pressing for solid-dosage forms, such as micropellets.This masterclass reviews HME technology, particularly using twin-screw extruders and illustrates its advantages for pharmaceutical applications. Starting with the initial mixing of APIs, this interactive session will move sequentially through processing, cooling, milling and final pressing for solid-dosage forms, such as micropellets.   Who should attend?Process engineersLab managersR & D engineersHeads of R & DHeads of productionProduction engineersProject managersSales managersSales engineersBy attending this meeting, you will:Understand the hot-melt extrusion process from first principles to final productAcquire the insights to employ continuous compounding in productionEvaluate the advantages of twin-screw extruder technology compared to single-screw methodsUtilise process development analyticsContextualise the business case for HME in pharmaceutical manufacturingContact Fateja Begum