Today, nanoparticles are widely implemented as functional elements on surfaces, into volumes and as nanohybrids, resulting for example in bioactive composites and nanobiomarkers. Nowadays, however, only a limited variety of materials that may be integrated into advanced functional materials are available: Nanoparticles synthesized by conventional gas phase processes are often agglomerated to micro powders that are hardly redispersible into functional matrices, and chemical methods often lead to impurities of the nanoparticle colloids caused by additives and precursor reaction products.In the last decade, laser ablation and nanoparticle generation in liquids has proven to be a unique and efficient technique to generate, excite, fragment, and conjugate elemental, nano-alloy, semiconductor and ceramic nanoparticles. This exciting method bears strong advantages:Laser-generated (metal) nanoparticles are charged and thus have an extremely high colloidal stability.In contrary to dry nanopowders, nanoparticle colloids are not inhalable and thus lead to an improved occupational safety.Chemical precursors are not required and thus the colloids are 100% pure.This method can be applied universally with an almost unlimited variety of materials and solvents.It recently has been shown that these advantages are of value in comparison to conventional synthesis, in particular:A 3-5 times higher number of biomolecules may be conjugated to laser-generated, ligand-free gold nanoparticle surface.Higher yields of laser-generated gold nanoparticle aptamer conjugates are beneficial especially if costly functional biomolecules are conjugated.Lower noise during surface enhanced Raman scattering of laser-generated pure nanoparticles.Ablation in polymer solution allows embedding into polymer matrices for rapid nanomaterial prototyping. The first edition of this conference, ANGEL 2010, welcomed 80 attendees from 25 countries. Following up on ANGEL 2010, aspects of the fundamentals of laser ablation in liquids as well as novel applications will be discussed at ANGEL 2012. TopicsModeling and fundamentals of laser ablation and particle fragmentation in liquidsNano-alloys, core-shell particleNano-hybrids, conjugation with organic molecules and biomoleculesLaser-generated nano-compositesLaser nanoparticle heating / phototherapyPulsed laser optoporation with nanoparticlesNanoparticle productivity / scale-upAbstract submission deadline: 3 February 2012Early-bird registration deadline: 6 April 2012